IC MP Content Guide and Sample Questions Part 2: NMP

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Nuclear Medical Physics (NMP) Content Guide

Part 2 Content Guide and Sample Questions

The content of all ABR exams is determined by a panel of experts who select the items based on a content guide that the ABR publishes. The content guides are assembled using guidance from medical physics organizations. The content guides are general documents, and individual exam items may not appear to be exactly congruent with the content listed in the guide. In addition, since there is only a limited number of items on any exam, selected items will only be a sample from the larger domain of the content guide.

PLEASE NOTE: List of Constants and Physical Values for Use on the Part 2 Physics Exams

The ABR provides candidates with a list of constants, physical values, and related information, which can be found on this page. While the list includes many constants and physical values, the ABR does not warrant the list as a compilation of all constants and physical values needed on the examinations. Candidates should review the list carefully before their examinations to familiarize themselves with the contents and list organization.


  1. Radiation Protection, Safety, Professionalism, and Ethics
    • Internal dosimetry
    • Dose terminology and Definitions
    • Dose Regulations
    • Expected doses
    • Fetal Dosimetry
    • CT dosimetry
    • Occupational safety
    • Safety for the patient, family and public
    • Time, distance shielding
    • Shielding calculations
    • Professionalism and Ethics
  1. PET & Hybrid
    • Basic PET scanner Instrumentation
    • Radionuclide production and characteristics
    • PET Detectors
    • Acquisition
    • Reconstruction
    • Corrections (Attenuation, random, scatter)
    • Quantitative PET
    • PET/CT
    • QC procedures
    • Acceptance/Annual testing
  2. Single photon imaging systems including scintillation cameras, solid state cameras and hybrids
    • Basic system instrumentation
    • Radionuclide production and characteristics
    • Intrinsic Specifications
    • Extrinsic Specifications
    • Collimation
    • Digital Systems
    • Dynamic imaging
    • SPECT
    • SPECT/CT
    • QC procedures
    • Acceptance/Annual testing
  3. Radiation measurements including dose calibrators, well counters, survey meters, thyroid probes
    • Scintillation detector system
    • Solid State Detectors
    • Well Counters and Probes
    • Survey Meters
    • Dose Calibrator
    • Dead-time
    • Efficiency
    • Operation of SCA, MCA
    • Statistical distributions
    • Statistical Tests
    • Propagation of Errors
    • Digital Image Statistics
    • Chi-Square Tests
    • Minimum detectable activity
    • Quantitative measurements including calibration
    • Quality Control
  4. Clinical Procedures  
    • Cardiac
    • Pulmonary
    • Tumor Imaging
    • Bone Imaging
    • Brain
    • Endocrine (Thyroid)
    • Lymphatic
    • Radionuclide therapy
    • Brachytherapy
    • Other


SAMPLE QUESTIONS  (includes new item types)


Simple Questions

1. How are 201TI and 123I produced?

A. In fission by-products
B. In particle accelerators
C. In radionuclide generators
D. In neutron activation

2. A spatial resolution measurement of a SPECT system is performed using line sources of 99mTc according to the NEMA protocol. If the spatial resolution (FWHM) is 10.5 mm in the center of the phantom, what is the peripheral tangential spatial resolution (FWHM) at 7.5 cm from the center of the phantom?

A.8 mm
B.12 mm
C.14 mm
D.16 mm 

3. What is the effect of increasing an image matrix from 128 x 128 to 256 x 256?

A. Improved contrast
B. Improved resolution
C. Improved signal-to-noise ratio
D. Decreased noise

4. If the minimum, mean, and maximum pixel counts in the central field of view of a smoothed intrinsic flood image are 4500, 5200, and 5500, respectively, what is the integral uniformity?

A.   5%
B.   6%
C.  10%
D.  14%
E.  15%

5. In a gate-synchronized ventricular function study, the color-coded phase image shows a group of pixels in the apex of the left ventricle displayed in the hue assigned to the atria. What is the most likely explanation for this observation?  

A. Global left ventricular hypokinesis  
B. Valvular insufficiency  
C. Malfunctioning software
D. Cardiac arrhythmia
E. Apical dyskinesis

Answers for this section:   

1. B
2. A
3. B
4. C
5. E

New Item Types:

Multiple Correct Options

The candidate must select all of the correct options for each item:

1. According to AAPM Report No. 181, what are the three required QC tests on a dose calibrator? (Please select three options.)

A. Constancy
B. Geometric calibration
C. Uniformity
D. Linearity
E. Accuracy
F. Chi-square

Answer: A, D, and E

Fill in the Blank
The candidate must type in the correct response:

1. If the field of view of a scintillation camera is 20 cm and the matrix is 128 × 128, what is the pixel size of the image? ____________ mm (Round to two decimal places.)

Answer: 1.56, (1.54, 1.55, 1.56, 1.57, and 1.58 will also be accepted.)

For each question, choose the correct radiopharmaceutical from the drop-down list. Each option can be used once, more than once, or not at all. Please advance to the next screen.

A. 111In leukocytes
B. 111In pentetate (DTPA)
C. 123I ioflupane
D. 123I NaI
E. 99mTc MAA
F. 99mTc MDP
G. 99mTc sestamibi

1. This radiopharmaceutical is used primarily for the diagnosis of infection.
2. This radiopharmaceutical is used primarily for the diagnosis of thyroid function.
3. This radiopharmaceutical is used primarily for the diagnosis of pulmonary embolism.


1. A
2. D
3. E


1. The figure shows a common device employed in nuclear radiology instrumentation. Point and click on the cathode.

Answer: The candidate can click anywhere within the yellow oval.



Complex Questions

1. A 99mTc radioactive tracer is removed from the kidneys by three pathways: 1) absorption in the blood at 50% every 3 hours; 2) excretion to the bladder at 50% every 2 hours; and 3) physical decay. How long is the effective half-time of the radioactive tracer in the kidney?

    A. 1 hour
    B.  2 hours
    C. 4 hours
    D. 6 hours
    E. 11 hours

2. A generator is eluted and yields 300 mCi of 99mTc. For clinical studies to be done up to 6 hours after elution, what is the maximum acceptable number of microcuries of 99Mo allowable at the time of elution?

    A. 5.6 μCi
    B. 12 μCi
    C. 24 μCi
    D. 30 μCi
    E. 45 μCi

3. If annihilation radiation originates in the center of the water-filled phantom diagrammed below, what will be the PET attenuation correction factor? (µ = 0.096 cm -1)

    A. 15.9
    B. 24.1
    C. 31.7
    D. 40.3
    E. 48.5


4. A χ2 test is performed with a sample size of 10, using a long-lived source. The following results are obtained: 

Standard Deviation = 205.5
Mean = 3752.6

What is the χ2 value?

A.  14.3
B.  101
C.  205
D.  3753
E.  42,256 

5. The following intrinsic line spread function is recorded using a slit phantom:

Channel #


133 300
134 400
135 580
136 675
137 780
138 900
139 950
140 1000
141 970
142 911
143 833
144 710
145 560
146 480
147 345

The distance per channel is 0.4 mm. What is the intrinsic spatial resolution (FWHM)?

A.  3.48 mm
B.  3.75 mm
C.  4.28 mm
D.  4.48 mm
E.  6.50 mm

Answers for this section: 

  1. A
  2. C
  3. C
  4. B
  5. D